Methimazole Information
Pronunciation
(meth IM a zole)
What is this drug used for?
– It is used to treat an overactive thyroid gland.
Frequently reported side effects of this drug
– Headache
– Itching
– Change in taste
– Fatigue
– Muscle pain
– Joint pain
– Hair loss
– Skin discoloration
– Vomiting
– Nausea
Other side effects of this drug: Talk with your doctor right away if you have any of these signs of:
– Infection
– Liver problems like dark urine, fatigue, lack of appetite, nausea, abdominal pain, light-colored stools, vomiting, or yellow skin.
– Kidney problems like unable to pass urine, blood in the urine, change in amount of urine passed, or weight gain.
– Lupus like rash on the cheeks or other body parts, sunburn easy, muscle or joint pain, chest pain or shortness of breath, or swelling in the arms or legs.
– Low blood sugar like dizziness, headache, fatigue, feeling weak, shaking, fast heartbeat, confusion, increased hunger, or sweating.
– Shortness of breath
– Coughing up blood
– Burning or numbness feeling
– Swollen glands
– Bruising
– Bleeding
– Severe loss of strength and energy
– Edema
– Signs of a significant reaction like wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
Medication Safety Issues
Sound-alike/look-alike issues:
MethIMAzole may be confused with methazolAMIDE, metOLazone
Storage and Stability
Store at 15?C to 30?C (59?F to 86?F)
Adverse Reactions
Cardiovascular: Edema, periarteritis
Central nervous system: Drowsiness, drug fever, headache, neuritis, paresthesia, vertigo
Dermatologic: Alopecia, pruritus, skin pigmentation, skin rash, urticaria
Endocrine & metabolic: Hypoglycemic coma, hypothyroidism, insulin autoimmune syndrome
Gastrointestinal: Ageusia, enlargement of salivary glands, epigastric distress, nausea, vomiting
Hematologic & oncologic: Agranulocytosis, aplastic anemia, granulocytopenia, hypoprothrombinemia, leukopenia, lymphadenopathy, thrombocytopenia
Hepatic: Hepatitis, jaundice
Neuromuscular & skeletal: Arthralgia, lupus-like syndrome, myalgia
Renal: Nephritis
Rare but important or life-threatening: Acute hepatic failure, acute pancreatitis, acute renal injury, cerebral vasculitis, glomerulonephritis, hepatotoxicity, hypersensitivity angiitis, neuropathy, pulmonary alveolar hemorrhage, vasculitis (including ANCA positive)
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