Glynase XL (Glucotrol XL)5MG 100 tablet

Glipizide Information

What is this drug used for?

– It is used to lower blood sugar in patients with high blood sugar (diabetes).

Possible side effects

Glipizide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

– Dizziness.
– Diarrhea.
– Feeling nervous and excitable.
– Gas.

Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:

– Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
– Change in eyesight.
– Slurred speech.
– Tingling.
– Feeling very tired or weak.
– Low blood sugar can happen. The chance may be raised when this drug is used with other drugs for diabetes. Signs may be dizziness, headache, feeling sleepy or weak, shaking, fast heartbeat, confusion, hunger, or sweating. Call your doctor right away if you have any of these signs. Follow what you have been told to do for low blood sugar. This may include taking glucose tablets, liquid glucose, or some fruit juices.

Medication Safety Issues

Storage and Stability

Extended release: Store at 68?F to 77?F (20?C to 25?C); excursions permitted between 59?F to 86?F (15?C to 30?C). Protect from moisture and humidity.

Immediate release: Store below 30?C (86?F).

Adverse Reactions

Frequency not always defined.

Cardiovascular: Syncope (<3%)

Central nervous system: Dizziness (2% to 7%), nervousness (4%), anxiety (<3%), depression (<3%), hypoesthesia (<3%), insomnia (<3%), pain (<3%), paresthesia (<3%), drowsiness (2%), headache (2%)

Dermatologic: Diaphoresis (<3%), pruritus (1% to <3%), eczema (1%), erythema (1%), maculopapular rash (1%), morbilliform rash (1%), skin rash (1%), urticaria (1%)

Endocrine & metabolic: Hypoglycemia (<3%), increased lactate dehydrogenase

Gastrointestinal: Diarrhea (1% to 5%), flatulence (3%), dyspepsia (<3%), vomiting (<3%), constipation (1% to <3%), nausea (1% to <3%), abdominal pain (1%)

Hepatic: Increased serum alkaline phosphatase, increased serum AST

Neuromuscular & skeletal: Tremor (4%), arthralgia (<3%), leg cramps (<3%), myalgia (<3%)

Ophthalmic: Blurred vision (<3%)

Renal: Increased blood urea nitrogen, increased serum creatinine

Respiratory: Rhinitis (<3%)

1%, postmarketing, and/or case reports: Agranulocytosis, anorexia, aplastic anemia, bloody stools, cardiac arrhythmia, chills, cholestatic jaundice, confusion, conjunctivitis, decreased libido, disulfiram-like reaction, dyspnea, dysuria, edema, eye pain, flushing, hemolytic anemia, hepatic injury, hypertension, hypertonia, hyponatremia, jaundice, leukopenia, migraine, pancytopenia, pharyngitis, porphyria, retinal hemorrhage, SIADH (syndrome of inappropriate antidiuretic hormone secretion), skin photosensitivity, thrombocytopenia, unsteady gait, vertigo